Platinum & Palladium Nanoparticles (PtNPs) have shown potential in enhancing skin health and combating aging

Platinum and Palladium nanoparticles (Pt-Pd NPs) have shown potential in enhancing skin health and combating aging. Studies indicate that Pt - Pd NPs can promote collagen I biosynthesis in human foreskin fibroblasts (HFF-1 cells) by activating the TGF-β/Smad pathway, which is beneficial for skin health. Additionally, PtNPs exhibit strong catalytic activity, functioning as antioxidants by reducing intracellular reactive oxygen species (ROS) levels, which can help mitigate oxidative stress associated with aging.

Research also suggests that noble metals can protect against aging-related skin pathologies in mice by normalising gene expression levels of collagen type I (Col1a1), matrix metallopeptidase 2 (Mmp2), and hyaluronan synthase 2 (Has2), among others. These effects contribute to maintaining skin integrity and preventing thinning and atrophy.

In summary, platinum & palladium nanoparticles have potential applications in anti-aging skincare due to their antioxidant properties and ability to enhance collagen production. However, further research is necessary to fully understand their safety and optimal usage in dermatological applications.

References

• Palladium and Platinum Nanoparticles Attenuate Aging-Like Skin Atrophy via Antioxidant Activity in Mice

• Platinum nanoparticles in nanobiomedicine

• Green synthesis of platinum nanoparticles by Nymphaea tetragona flower extract and their skin lightening, antiaging effects

• A detailed review on biosynthesis of platinum nanoparticles (PtNPs), their potential antimicrobial and biomedical applications